Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ACLY | P53396 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17859653 | 0.80 | HPGD (0.49) | HPGDKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL6489248 | 0.78 | HPGD (0.42) | HPGDKDM4EMAPTALDH1A1ACLY | |
| SCHEMBL2568229 | 0.76 | HTR2C (0.48) | HPGDKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL6488354 | 0.76 | KDM4E (0.48) | HPGDKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL6497164 | 0.76 | PDCD1 (0.62) | HPGDKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL19760442 | 0.76 | KDM4E (0.48) | HPGDKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL27736542 | 0.75 | KDM4E (0.44) | HPGDKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL5036095 | 0.75 | NR1H4 (0.52) | LMNAHSD17B10GAAHTTKMT2A | |
| SCHEMBL13614235 | 0.74 | KDM4E (0.47) | HPGDKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL12474258 | 0.74 | AGXT (0.47) | ACLYKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |