SCHEMBL683181

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28506436	0.85	NPC1 (0.50)	NQO2ALDH1A1NPC1KDM4ERAB9A
	SCHEMBL681786	0.82	NQO2 (0.50)	NQO2ALDH1A1NPC1RAB9AMEN1
	SCHEMBL27497156	0.81	NQO2 (0.47)	NQO2ALDH1A1NPC1KDM4ERAB9A
	SCHEMBL2170898	0.78	PDE4B (0.50)	NQO2ALDH1A1NPC1KDM4ERAB9A
	SCHEMBL30527150	0.78	NQO2 (0.45)	NQO2ALDH1A1NPC1KDM4EPDE4A
	SCHEMBL2841461	0.78	NQO2 (0.45)	NQO2ALDH1A1NPC1KDM4ERAB9A
	SCHEMBL25903679	0.78	NQO2 (0.45)	NQO2ALDH1A1NPC1KDM4EPDE4A
	SCHEMBL683182	0.77	PDE4B (0.56)	PDE4APDE4BPDE4CPDE4D
	SCHEMBL4702849	0.77	PDE4A (0.48)	NQO2ALDH1A1NPC1KDM4ERAB9A
	SCHEMBL4704138	0.76	KDM4E (0.55)	NQO2ALDH1A1KDM4ERAB9APDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.