Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740486 | 0.88 | DRD4 (1.00) | DRD4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9080658 | 0.85 | DRD4 (0.80) | DRD4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6508504 | 0.81 | DRD4 (0.64) | DRD4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9269886 | 0.81 | DRD4 (0.80) | DRD4DRD2DRD3ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL8055367 | 0.81 | DRD4 (0.76) | DRD4DRD2DRD3GAA | |
| SCHEMBL9081182 | 0.80 | DRD4 (0.72) | DRD4DRD2DRD3PPARGGAA | |
| SCHEMBL3567676 | 0.80 | KMT2A (0.78) | DRD4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9269749 | 0.79 | DRD4 (0.83) | DRD4DRD2DRD3ADRA1DADRA1A | |
| SCHEMBL10390502 | 0.79 | DRD4 (0.75) | DRD4DRD2DRD3ADRA1DADRA1A | |
| SCHEMBL9269193 | 0.78 | DRD4 (0.80) | DRD4HDAC1DRD2DRD3ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096771-A1 | BIARYL COMPOUNDS HAVING ACTIVITY AT THE 5HT5A RECEPTOR | GLAXO GROUP LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |