Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | FAP | Q12884 | 9/20 | 0.81 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.79 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.68 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860819 | 1.00 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL3165078 | 1.00 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL5987446 | 1.00 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL356162 | 0.99 | DPP4 (0.98) | DPP4FAPDPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL295498 | 0.99 | DPP4 (0.98) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL3160316 | 0.90 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL3159890 | 0.90 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL8353910 | 0.90 | DPP4 (1.00) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL3156933 | 0.90 | DPP4 (1.00) | DPP4FAPDPP7 | |
| Hydrochloric Acid SCHEMBL3259953 | 0.89 | DPP4 (0.98) | DPP4FAPDPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092128-A1 | ANHYDROUS CRYSTALLINE FORMS OF (2S, 4S)-1-{(2R)-2-AMINO-3-‘4-METHOXYBENZYL)SULFONYL!-3-METHYLBUTANOYL}-4-FLUOROPYRROLINDINE-2-CARBONITRILE | SMITHKLINE BEECHAM CORPORATION (US) | 2004-10-28 | — | — | WO | claimed |
| WO-2004092128-A1 | ANHYDROUS CRYSTALLINE FORMS OF (2S, 4S)-1-{(2R)-2-AMINO-3-‘4-METHOXYBENZYL)SULFONYL!-3-METHYLBUTANOYL}-4-FLUOROPYRROLINDINE-2-CARBONITRILE | SMITHKLINE BEECHAM CORPORATION (US) | 2004-10-28 | — | — | WO | disclosed |