⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923490 | 1.00 | — | — | |
| SCHEMBL11372603 | 0.98 | — | — | |
| SCHEMBL11366760 | 0.98 | — | — | |
| SCHEMBL11374701 | 0.98 | — | — | |
| SCHEMBL11365002 | 0.93 | — | — | |
| SCHEMBL11384808 | 0.88 | — | — | |
| SCHEMBL11376807 | 0.84 | — | — | |
| SCHEMBL10676403 | 0.83 | — | — | |
| SCHEMBL10743687 | 0.83 | — | — | |
| SCHEMBL11375733 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | BRAINCELLS INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | BRAINCELLS INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-4839367-A | Antihypertensive amide compounds | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| US-4766210-A | Antihypertensive lactams | SUH JOHN T (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0100053-B1 | COMPOUNDS HAVING ANGIOTENSIN CONVERTING ENZYME INHIBITORY ACTIVITY AND DIURETIC ACTIVITY | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1987-10-21 | — | — | EP | disclosed |
| US-4661515-A | N-CYCLOPENTYL GLYCINE DERIVATIVES | USV PHARMACEUTICAL CORPORATION (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0066254-B1 | MERCAPTO AMINO ACIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | USV PHARMACEUTICAL CORPORATION (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4619944-A | AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0040332-B1 | ANTIHYPERTENSIVE LACTAMS | USV PHARMACEUTICAL CORPORATION (US) | 1986-09-17 | — | — | EP | disclosed |
| US-4507316-A | Antihypertensive compounds | USV PHARMACEUTICAL CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| EP-0100053-A1 | Compounds having angiotensin converting enzyme inhibitory activity and diuretic activity | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1984-02-08 | — | — | EP | disclosed |
| EP-0066254-A1 | Mercapto amino acids, process for their preparation and pharmaceutical compositions containing them | USV PHARMACEUTICAL CORPORATION (US) | 1982-12-08 | — | — | EP | disclosed |
| EP-0040332-A1 | Antihypertensive lactams | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-25 | — | — | EP | disclosed |
| US-4287203-A | Antihypertensive 1,4-thiazepine-ones, 1,4-thiazonine-ones, and method of use thereof | USV PHARMACEUTICAL CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |
| US-4256761-A | Antihypertensive amides | USV PHARMACEUTICAL CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |