Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4476941 | 0.97 | MAPK14 (0.45) | MAPK14MAPKAPK2PTGER1 | |
| SCHEMBL4474772 | 0.97 | MAPK14 (0.45) | MAPK14MAPKAPK2PTGER1 | |
| SCHEMBL4468368 | 0.96 | MAPK14 (0.46) | MAPK14MAPKAPK2PTGER1 | |
| SCHEMBL4478104 | 0.96 | MAPK14 (0.46) | MAPK14MAPKAPK2PTGER1 | |
| SCHEMBL5861917 | 0.94 | MAPK14 (0.48) | MAPK14MAPKAPK2PTGER1 | |
| SCHEMBL4477099 | 0.93 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL4485548 | 0.93 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL4477064 | 0.91 | MAPK14 (0.46) | MAPK14MAPKAPK2PTGER1 | |
| SCHEMBL4478822 | 0.91 | MAPK14 (0.46) | MAPK14MAPKAPK2PTGER1 | |
| SCHEMBL4466224 | 0.90 | MAPK14 (0.45) | MAPK14MAPKAPK2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058964-A1 | Substituted pyridinones | PHARMACIA LLC | 2004-03-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058964-A1 | Substituted pyridinones | MAPK1, MAPK6, MAPK7 | MAPK14 41/4885MAPKAPK2 25/4885PTGER1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.