⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27552601 | 0.89 | HIF1A (0.43) | — | |
| SCHEMBL7598577 | 0.84 | — | — | |
| SCHEMBL18373355 | 0.75 | — | — | |
| SCHEMBL944728 | 0.73 | — | — | |
| SCHEMBL562973 | 0.70 | — | — | |
| SCHEMBL1859356 | 0.70 | — | — | |
| SCHEMBL4143588 | 0.70 | — | — | |
| SCHEMBL4143585 | 0.70 | — | — | |
| SCHEMBL6355721 | 0.70 | — | — | |
| SCHEMBL18984256 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116622088-A | Nitrogen and phosphorus-containing graphene synergistic flame retardant, and preparation method and application thereof | 昆明伴文新材料科技有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-100427189-C | Method for producing selective diffusion barrier with excellent pollution resistibility | SAE HAN INDUSTRY CO LTD (KR) | 2008-10-22 | — | — | CN | claimed |
| CN-1318542-A | Synthesis of piperazine and its derivative | FUKANGLAI SCIENCE & TECHNOLOGY (CN) | 2001-10-24 | — | — | CN | claimed |
| JP-57126871-A | — | — | None | — | — | JP | disclosed |
| JP-57126860-A | — | — | None | — | — | JP | disclosed |
| CN-116622088-A | Nitrogen and phosphorus-containing graphene synergistic flame retardant, and preparation method and application thereof | 昆明伴文新材料科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-115702189-A | Composition containing thermally conductive filler | PPG工业俄亥俄公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-111057060-B | Synthesis process of composite piperazine heavy metal chelating agent TDDP | 烟台中科荣达新材料有限公司 | 2021-09-21 | — | — | CN | disclosed |
| WO-2021129155-A1 | PROCESS FOR SYNTHESIZING COMPOSITE PIPERAZINE-BASED HEAVY METAL CHELATING AGENT TDDP | 烟台中科荣达新材料有限公司 | 2021-07-01 | — | — | WO | disclosed |
| CN-108558258-B | Preparation method and application of 2, 5-dimethylpiperazine derivative and cement additive | 南京红宝丽醇胺化学有限公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-111057060-A | Synthesis process of composite piperazine heavy metal chelating agent TDDP | 青岛中科荣达新材料有限公司 | 2020-04-24 | — | — | CN | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| CN-1318542-A | Synthesis of piperazine and its derivative | FUKANGLAI SCIENCE & TECHNOLOGY (CN) | 2001-10-24 | — | — | CN | disclosed |
| US-5928393-A | ESTERIFIED, ALKOXYLATED TERTIARY AMINE COMPOUND; DETERGENT ANTISLUDGE/ANTIDEPOSIT AGENT FOR INTERNAL COMBUSTION ENGINES | NIPPON OIL CO., LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0819753-A1 | Fuel additive | NIPPON OIL CO. LTD. (JP) | 1998-01-21 | — | — | EP | disclosed |
| US-4539405-A | EXPOLSIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1985-09-03 | — | — | US | disclosed |
| JP-S57126860-A | AQUEOUS THERMOSETTING COAT COMPOSITION | DAINIPPON INK & CHEM INC | 1982-08-06 | — | — | JP | disclosed |
| JP-S57126871-A | CATIONIC ELECTRODEPOSITING RESIN COMPOSITION | DAINIPPON INK & CHEM INC | 1982-08-06 | — | — | JP | disclosed |
| US-4049660-A | N-substituted derivatives of 4 (N-piperazinylmethyl) spiro dibenzocycloheptadi- (or tri-) ene-5, 2-dioxolane (1,3) their method of preparation and their application in therapeutics | DELALANDE S.A. (FR) | 1977-09-20 | — | — | US | disclosed |