Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.43 |
| ▸ | PPARA | Q07869 | 13/20 | 0.42 |
| ▸ | PPARD | Q03181 | 9/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081606 | 1.00 | PPARG (0.43) | PPARGPPARAPPARDCA12CA1 | |
| SCHEMBL4081609 | 1.00 | PPARG (0.43) | PPARGPPARAPPARDCA12CA1 | |
| SCHEMBL4081602 | 1.00 | PPARG (0.43) | PPARGPPARAPPARDCA12CA1 | |
| SCHEMBL13649262 | 0.92 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL4081639 | 0.92 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL4081634 | 0.92 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL4076691 | 0.92 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL4076700 | 0.92 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL4073182 | 0.89 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL4073175 | 0.89 | PPARG (0.47) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | claimed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | claimed |
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | disclosed |