Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 13/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458028 | 1.00 | EPHX1 (0.43) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6867414 | 0.96 | EPHX1 (0.45) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6867421 | 0.96 | EPHX1 (0.45) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6463888 | 0.94 | EPHX1 (0.47) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6463884 | 0.94 | EPHX1 (0.47) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6465107 | 0.90 | MCHR1 (0.40) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6465098 | 0.90 | MCHR1 (0.40) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6463985 | 0.89 | MCHR1 (0.43) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6463994 | 0.89 | MCHR1 (0.43) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6459826 | 0.88 | EPHX1 (0.46) | EPHX1MCHR1ADRA2AHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | claimed |
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | claimed |
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |