Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.42 |
| ▸ | SYK | P43405 | 8/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 6/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 4/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.34 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455574 | 0.84 | MCHR1 (0.51) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6456487 | 0.79 | MCHR1 (0.49) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6464501 | 0.77 | MCHR1 (0.45) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6456500 | 0.75 | MCHR1 (0.47) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6456465 | 0.71 | MCHR1 (0.47) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6459587 | 0.70 | MCHR1 (0.52) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6461142 | 0.70 | MCHR1 (0.48) | MCHR1SYKADRA2AADRA1AHRH1 | |
| SCHEMBL6455417 | 0.70 | MCHR1 (0.56) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| Trifluoroacetic Acid SCHEMBL6833473 | 0.69 | MCHR1 (0.67) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| Trifluoroacetic Acid SCHEMBL6455569 | 0.69 | MCHR1 (0.67) | MCHR1ADRA2AADRA1AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |