Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MYC | P01106 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13254359 | 0.87 | IDO1 (0.56) | MEN1KMT2ANPC1RAB9AHSPB1 | |
| SCHEMBL18895765 | 0.87 | IDO1 (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL18896943 | 0.87 | IDO1 (0.63) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL18895762 | 0.87 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL18895768 | 0.87 | IDO1 (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL18895763 | 0.87 | IDO1 (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL18895764 | 0.87 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL3504074 | 0.87 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1IDO1 | |
| SCHEMBL26106550 | 0.86 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL18895772 | 0.85 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6749645-B2 | RED AND BLUE DIRECT DYE; HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | claimed |
| EP-1317242-A1 | USE OF 4-NITRO-2,1,3-BENZOXADIAZOL DERIVATIVES AS DYES IN COLOURING AGENTS FOR KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-06-11 | — | — | EP | claimed |
| US-20020189032-A1 | Use of 4-nitro-2,1,3,-benzoxadiazole derivatives as dyes in colouring agents for keratin fibres | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-12-19 | — | — | US | claimed |
| WO-2002022094-A1 | USE OF 4-NITRO-2,1,3-BENZOXADIAZOL DERIVATIVES AS DYES IN COLOURING AGENTS FOR KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | claimed |
| US-9664696-B1 | Compounds for determining the presence of hydrogen sulfide and methods of use | UNIVERSITY OF OREGON (US) | 2017-05-30 | — | — | US | disclosed |
| US-9664696-B1 | Compounds for determining the presence of hydrogen sulfide and methods of use | UNIVERSITY OF OREGON (US) | 2017-05-30 | — | — | US | disclosed |
| US-6749645-B2 | RED AND BLUE DIRECT DYE; HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | disclosed |
| EP-1317242-A1 | USE OF 4-NITRO-2,1,3-BENZOXADIAZOL DERIVATIVES AS DYES IN COLOURING AGENTS FOR KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-06-11 | — | — | EP | disclosed |
| US-20020189032-A1 | Use of 4-nitro-2,1,3,-benzoxadiazole derivatives as dyes in colouring agents for keratin fibres | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-12-19 | — | — | US | disclosed |
| WO-2002022094-A1 | USE OF 4-NITRO-2,1,3-BENZOXADIAZOL DERIVATIVES AS DYES IN COLOURING AGENTS FOR KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020189032-A1 | Use of 4-nitro-2,1,3,-benzoxadiazole derivatives as dyes in colouring agents for keratin fibres | CBR1, CYC1, CBR3 | MEN1 4392/4885KMT2A 2588/4885NPC1 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.