Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.40 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267348 | 0.92 | MAP2K1 (0.48) | MAP2K1TDP1AURKATNFRSF1AMAP3K9 | |
| SCHEMBL6261655 | 0.86 | MAP2K1 (0.56) | MAP2K1TDP1HDAC3HDAC1HDAC7 | |
| SCHEMBL6260604 | 0.84 | HDAC8 (0.48) | MAP2K1TDP1AURKATNFRSF1AMAP3K9 | |
| SCHEMBL6262801 | 0.81 | MAP2K1 (0.60) | MAP2K1AURKATNFRSF1AMAP3K9KDR | |
| SCHEMBL6263453 | 0.79 | HDAC8 (0.51) | DHODHHDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL6263489 | 0.78 | MAP2K1 (0.58) | MAP2K1TDP1HDAC3HDAC1HDAC7 | |
| SCHEMBL6261443 | 0.78 | MAP2K1 (0.49) | MAP2K1APPAURKATNFRSF1AMAP3K9 | |
| SCHEMBL6260594 | 0.78 | MAP2K1 (0.49) | MAP2K1AURKATNFRSF1AMAP3K9KDR | |
| SCHEMBL6261594 | 0.78 | MAP2K1 (0.49) | MAP2K1AURKATNFRSF1AMAP3K9KDR | |
| SCHEMBL6266866 | 0.77 | MEN1 (0.61) | MAP2K1TDP1HDAC3HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6750217-B2 | ANTICANCER AGENTS; CARDIOVASCULAR DISORDERS; KINASE INHIBITOR | WARNER-LAMBERT COMPANY | 2004-06-15 | — | — | US | disclosed |