Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913695 | 0.78 | KDM1A (0.38) | KDM1AMEN1KMT2AGAANOS2 | |
| SCHEMBL21155963 | 0.75 | KDM1A (0.32) | KDM1AMEN1KMT2AGAACREBBP | |
| SCHEMBL30570961 | 0.73 | BRD4 (0.50) | MEN1KMT2AGAACREBBPBRD4 | |
| SCHEMBL15508279 | 0.73 | BRD4 (0.50) | MEN1KMT2AGAACREBBPBRD4 | |
| SCHEMBL29898376 | 0.73 | BRD4 (0.50) | MEN1KMT2AGAACREBBPBRD4 | |
| SCHEMBL12837030 | 0.73 | MEN1 (0.34) | MEN1KMT2AGAACREBBPBRD4 | |
| SCHEMBL5803889 | 0.73 | MEN1 (0.35) | MEN1KMT2AGAACREBBPBRD4 | |
| SCHEMBL2723593 | 0.73 | BRD4 (0.50) | MEN1KMT2AGAACREBBPBRD4 | |
| SCHEMBL19225173 | 0.73 | BRD4 (0.50) | MEN1KMT2AGAACREBBPBRD4 | |
| SCHEMBL728157 | 0.73 | MEN1 (0.35) | MEN1KMT2AGAAEPHX2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6679923-B2 | HAIR DYEING FORMULATION CONTAINING PYRAZOLIN-4,5-DIONES AND AT LEAST ONE AROMATIC PRIMARY AMINE ENABLES THE DYEING OF KERATIN FIBERS WITHOUT AND OXIDIZING AGENT IN SHADES WHICH ARE STRONG, VARIED, RESISTANT AND LESS SELECTIVE | L'OREAL S.A. (FR) | 2004-01-20 | — | — | US | claimed |
| US-20020194685-A1 | Composition for dyeing keratin fibres, comprising a pyrazoline-4, 5-dione and an aromatic primary amine | L'OREAL S.A. (FR) | 2002-12-26 | — | — | US | claimed |
| US-6464732-B2 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | claimed |
| US-20020040508-A1 | COMPOSITION FOR DYEING KERATIN FIBRES,COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL S.A. (FR) | 2002-04-11 | — | — | US | claimed |
| EP-0981320-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL (FR) | 2000-03-01 | — | — | EP | claimed |
| WO-1998051268-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL (FR) | 1998-11-19 | — | — | WO | claimed |
| US-6679923-B2 | HAIR DYEING FORMULATION CONTAINING PYRAZOLIN-4,5-DIONES AND AT LEAST ONE AROMATIC PRIMARY AMINE ENABLES THE DYEING OF KERATIN FIBERS WITHOUT AND OXIDIZING AGENT IN SHADES WHICH ARE STRONG, VARIED, RESISTANT AND LESS SELECTIVE | L'OREAL S.A. (FR) | 2004-01-20 | — | — | US | disclosed |
| US-20020194685-A1 | Composition for dyeing keratin fibres, comprising a pyrazoline-4, 5-dione and an aromatic primary amine | L'OREAL S.A. (FR) | 2002-12-26 | — | — | US | disclosed |
| US-6464732-B2 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | disclosed |
| US-20020040508-A1 | COMPOSITION FOR DYEING KERATIN FIBRES,COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL S.A. (FR) | 2002-04-11 | — | — | US | disclosed |
| EP-0981320-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL (FR) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998051268-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL (FR) | 1998-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020194685-A1 | Composition for dyeing keratin fibres, comprising a pyrazoline-4, 5-dione and an aromatic primary amine | KRT18, KLK5, MARK1 | KDM1A 105/4885MEN1 3401/4885KMT2A 1376/4885 |
| US-20020040508-A1 | COMPOSITION FOR DYEING KERATIN FIBRES,COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | KRT18, KLK5, H1-5 | KDM1A 146/4885MEN1 3896/4885KMT2A 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.