SCHEMBL6835124

SCHEMBL6835124

CC(=O)C(=NO)c1ccc(OCc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.74
NR4A2 P43354 2/20 0.68
MAPT P10636 2/20 0.60
HTT P42858 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
FFAR1 O14842 1/20 0.58
FFAR4 Q5NUL3 1/20 0.58
MRGPRX4 Q96LA9 2/20 0.55
ADCYAP1R1 P41586 1/20 0.52
POLB P06746 1/20 0.52
MAOA P21397 1/20 0.51
PDGFRA P16234 1/20 0.51
S1PR1 P21453 1/20 0.51
S1PR5 Q9H228 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6835123 1.00 MAOB (0.74) MAOBNR4A2MAPTHTTL3MBTL1
SCHEMBL7472529 0.87 MAOB (0.76) MAOBNR4A2MAPTHTTL3MBTL1
SCHEMBL7472525 0.87 MAOB (0.76) MAOBNR4A2MAPTHTTL3MBTL1
SCHEMBL7257895 0.85 MAOB (0.81) MAOBNR4A2MAPTHTTL3MBTL1
SCHEMBL20463439 0.85 MAOB (1.00) MAOBNR4A2MAPTHTTL3MBTL1
SCHEMBL7466482 0.85 MAOB (0.62) MAOBNR4A2MAPTHTTL3MBTL1
SCHEMBL7467631 0.85 MAOB (0.62) MAOBNR4A2MAPTHTTL3MBTL1
SCHEMBL6839176 0.83 MAOB (0.63) MAOBNR4A2MAPTHTTL3MBTL1
SCHEMBL6839169 0.83 MAOB (0.63) MAOBNR4A2MAPTHTTL3MBTL1
SCHEMBL6839961 0.83 MAOB (0.63) MAOBNR4A2MAPTHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040039220-A1 Process for the preparation of pesticides FAROOQ SALEEM (CH) 2004-02-26 US disclosed
US-6646151-B1 Efficient oximation BAYER AKTIENGESELLSCHAFT (DE) 2003-11-11 US disclosed
CN-1111155-C Process for preparation of pesticides BAYER AG (DE) 2003-06-11 CN disclosed
EP-0876333-B1 PROCESS FOR THE PREPARATION OF PESTICIDES BAYER AG (DE) 2002-03-27 EP disclosed
US-6156923-A Process for the preparation of pesticides NOVARTIS CORPORATION (US) 2000-12-05 US disclosed
CN-1203584-A Process for preparation of pesticides NOVARTIS AG (CH) 1998-12-30 CN disclosed
EP-0876333-A1 PROCESS FOR THE PREPARATION OF PESTICIDES Novartis AG (CH) 1998-11-11 EP disclosed
WO-1997020808-A1 PROCESS FOR THE PREPARATION OF PESTICIDES NOVARTIS AG (CH) 1997-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040039220-A1 Process for the preparation of pesticides CHRM1, CHRM2, F7 MAOB 28/4885NR4A2 1581/4885MAPT 792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.