SCHEMBL6835472

SCHEMBL6835472

C[Si](C)=[Zr](C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
NFKB1 P19838 1/20 0.35
CHRM3 P20309 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
THPO P40225 1/20 0.35
OPRK1 P41145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29480015 1.00 HTR2A (0.38) HTR2AKDM4ELMNATP53CHRM2
Bromide SCHEMBL8754748 0.98 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL8754916 0.98 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
Hydrochloric Acid SCHEMBL7646564 0.98 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
Hydrochloric Acid SCHEMBL8755059 0.96 HTR2A (0.36) HTR2AKDM4ELMNATP53CHRM2
Methyl Alcohol SCHEMBL7766791 0.96 HTR2A (0.36) HTR2AKDM4ELMNATP53CHRM2
Dimethylamine SCHEMBL7169462 0.95 KDM4E (0.39) HTR2AKDM4ELMNATP53CHRM2
Dimethylamine SCHEMBL7934339 0.93 KDM4E (0.41) HTR2AKDM4ELMNATP53CHRM2
Phenol SCHEMBL23273226 0.90 CA12 (0.34) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL30424841 0.88 HTR2A (0.33) HTR2AKDM4ELMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834514-B1 Process for synthesizing metallocene compounds KANTO KAGAKU (JP) 2003-10-22 EP claimed
US-11643533-B2 Film, method of producing film, and bag SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-09 US disclosed
US-11472899-B2 Ethylene-α-olefin copolymer, method of producing ethylene-α-olefin copolymer, ethylene-based resin composition, and film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-10-18 US disclosed
US-6753378-B2 GRAFTED WITH CARBOXYL- OR ANHYDRIDE CONTAINING COMPOUND; MELT PROCESSABILITY, CHEMICAL RESISTANCE, ELECTRICAL AND MECHANICAL PROPERTIES; INJECTION AND BLOW MOLDING; FILMS, SHEETS MITSUI CHEMICALS, INC. (JP) 2004-06-22 US disclosed
EP-1114832-B1 Modified particles, catalyst for olefin polymerization using the same, and process of producing olefin polymer SUMITOMO CHEMICAL CO (JP) 2003-10-22 EP disclosed
US-20030092845-A1 Ethylene copolymer composition TAKAHASHI MAMORU (JP) 2003-05-15 US disclosed
US-20020165322-A1 Ethylene copolymer composition TAKAHASHI MAMORU (JP) 2002-11-07 US disclosed
EP-0841373-B1 Propylene polymer compositions MITSUI CHEMICALS INC (JP) 2002-07-24 EP disclosed
EP-0678530-B1 Process for production of cyclic olefin copolymers and copolymers produced by said process MITSUI CHEMICALS INC (JP) 2001-07-25 EP disclosed
EP-0719803-B1 Process for the production of cycloolefin random copolymer MITSUI CHEMICALS INC (JP) 2001-03-21 EP disclosed
US-5650471-A COPOLYMERIZING AN ALPHA-OLEFIN AND A CYCLOOLEFIN IN THE PRESENCE OF A CATALYST FORMED FROM A TRANSITION METAL COMPOUND AND AN ORGANIC ALUMINUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-22 US disclosed
US-5574100-A ALPHA-OLEFIN-CYCLIC OLEFIN COPOLYMER, BUTADIENE-STYRENE COPOLYMER CORE, ALICYCLIC ACRYLATE SHELL MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-11-12 US disclosed
US-5559199-A MOLECULAR WEIGHT CONTROL MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-24 US disclosed
EP-0729983-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-04 EP disclosed
EP-0719803-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-07-03 EP disclosed
EP-0710663-A1 Boron-containing compound, its polymer, catalyst comprising the polymer and metallocene compound, and process for producing polyolefin Japan Polyolefins Co., Ltd. (JP) 1996-05-08 EP disclosed
US-5476903-A Composition containing copolymer of alpha-olefin and polyene with another polyolefin polymerized in presence of prepolymerized catalyst containing said copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-19 US disclosed
EP-0678530-A1 Process for production of cyclic olefin copolymers and copolymers produced by said process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-10-25 EP disclosed
EP-0634421-A1 Process for gas phase polymerization of olefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-01-18 EP disclosed
US-5371146-A A blends of ethylene-(alpha)olefins copolymers has high transparency, high strength, blocking resistance, good melt flowability and tension MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed