Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.36 |
| ▸ | HMGCR | P04035 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614496 | 0.93 | — | — | |
| SCHEMBL11563312 | 0.84 | TSHR (0.54) | TSHRPTPN7HMGCRKMT2AMAPT | |
| SCHEMBL20184219 | 0.84 | TSHR (0.48) | TSHRPTPN7HMGCRKMT2AMAPT | |
| SCHEMBL8663105 | 0.83 | — | — | |
| SCHEMBL38650663 | 0.83 | KMT2A (0.57) | TSHRTDP1PTPN7HMGCRKMT2A | |
| SCHEMBL8007919 | 0.80 | MCL1 (0.39) | TSHRTDP1KMT2AMAPTMEN1 | |
| SCHEMBL9331478 | 0.80 | TSHR (0.54) | TSHRTDP1PTPN7HMGCRKMT2A | |
| SCHEMBL12673292 | 0.80 | TDP1 (0.60) | TSHRTDP1KMT2AMAPTMEN1 | |
| SCHEMBL11589877 | 0.78 | TSHR (0.41) | TSHRTDP1KMT2AMAPTMEN1 | |
| SCHEMBL6257072 | 0.77 | PTPN7 (0.41) | TSHRTDP1PTPN7HMGCRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040030093-A1 | Metal catalyst for ring-opening polymerization of heterocyclic compound | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1340780-A1 | METAL CATALYST FOR RING-OPENING POLYMERIZATION OF HETEROCYCLIC COMPOUND | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030093-A1 | Metal catalyst for ring-opening polymerization of heterocyclic compound | MAX, PCNA, POLM | TSHR 4013/4885TDP1 4125/4885PTPN7 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.