Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.80 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.80 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371630 | 0.93 | ADORA2A (0.83) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4371641 | 0.93 | ADORA2A (0.83) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5723755 | 0.92 | ADORA2A (0.89) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7244182 | 0.92 | ADORA2A (0.89) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4368841 | 0.91 | ADORA2A (0.81) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4368838 | 0.91 | ADORA2A (0.81) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6831924 | 0.91 | ADORA2A (0.81) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5723698 | 0.91 | ADORA2A (0.79) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5723694 | 0.91 | ADORA2A (0.79) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4371495 | 0.91 | ADORA2A (0.81) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753322-B2 | 2-aminocarbonyl-9H-purine derivatives | PFIZER INC | 2004-06-22 | — | — | US | disclosed |