Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831686 | 0.81 | KDM4E (0.48) | ALDH1A1SMN1; SMN2KMT2ANPC1MAPT | |
| SCHEMBL6831684 | 0.77 | NPY5R (0.45) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL6836938 | 0.74 | NPY5R (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP11B2 | |
| SCHEMBL6567123 | 0.73 | NPY5R (0.41) | ALDH1A1CD274SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL6834554 | 0.72 | NPY5R (0.47) | SMN1; SMN2NPC1RAB9ATP53KDM4E | |
| SCHEMBL6831683 | 0.71 | NPY5R (0.44) | ALDH1A1SMN1; SMN2KMT2ANPC1MAPT | |
| SCHEMBL6834506 | 0.70 | NPY5R (0.48) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL6835176 | 0.67 | NPY5R (0.51) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6835192 | 0.65 | NPY5R (0.50) | ALDH1A1CYP11B2 | |
| SCHEMBL6835207 | 0.65 | CYP2A6 (0.35) | ALDH1A1KMT2AMAPTMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | H1-0, H1-5, H1-3 | ALDH1A1 784/4885CD274 4281/4885PDCD1 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.