Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.64 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 9/20 | 0.47 |
| ▸ | METAP1 | P53582 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CBFB | Q13951 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835219 | 0.85 | NPY5R (0.68) | NPY5RIDO1METAP2METAP1NPC1 | |
| SCHEMBL6834518 | 0.85 | NPY5R (0.68) | NPY5RIDO1METAP2METAP1NPC1 | |
| SCHEMBL6835188 | 0.81 | NPY5R (0.61) | NPY5RNPC1RAB9AKMT2A | |
| SCHEMBL6836970 | 0.81 | NPY5R (0.64) | NPY5RIDO1KDM4EALDH1A1 | |
| SCHEMBL5945579 | 0.80 | NPY5R (0.46) | NPY5RIDO1METAP2METAP1NPC1 | |
| SCHEMBL6831691 | 0.77 | NPY5R (0.66) | NPY5RNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL6835593 | 0.71 | NPY5R (0.34) | NPY5RHPGDKDM4EALDH1A1 | |
| SCHEMBL6567123 | 0.71 | NPY5R (0.41) | NPY5RNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9368974 | 0.70 | NPY5R (0.60) | NPY5RMETAP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6834554 | 0.69 | NPY5R (0.47) | NPY5RNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | H1-0, H1-5, H1-3 | NPY5R 983/4885IDO1 198/4885METAP2 4294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.