Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837146 | 0.92 | TACR3 (0.81) | TACR3 | |
| SCHEMBL325894 | 0.88 | TACR3 (1.00) | TACR3 | |
| SCHEMBL10026142 | 0.88 | TACR3 (1.00) | TACR3 | |
| SCHEMBL6837063 | 0.87 | TACR3 (1.00) | TACR3 | |
| SCHEMBL1393950 | 0.87 | TACR3 (1.00) | TACR3 | |
| SCHEMBL10026140 | 0.87 | TACR3 (1.00) | TACR3 | |
| SCHEMBL1393922 | 0.87 | TACR3 (1.00) | TACR3 | |
| SCHEMBL7670985 | 0.86 | TACR3 (0.91) | TACR3 | |
| SCHEMBL326560 | 0.85 | TACR3 (1.00) | TACR3 | |
| SCHEMBL6837081 | 0.85 | TACR3 (1.00) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004207-A1 | (3 -METHYLPYRROLIDIN- 3 - YL) METHYL PYRIDINYL ETHER DERIVATIVES AND THEIR USE AS NK-3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-12 | — | — | WO | disclosed |