Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 9/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529131 | 0.81 | KDM1A (0.59) | KDM1AMAOB | |
| SCHEMBL18949392 | 0.81 | KDM1A (0.59) | KDM1AMAOB | |
| SCHEMBL15136623 | 0.81 | KDM1A (0.59) | KDM1AMAOB | |
| SCHEMBL529132 | 0.81 | KDM1A (0.59) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL528687 | 0.80 | KDM1A (0.58) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL15137049 | 0.80 | KDM1A (0.58) | KDM1AMAOB | |
| SCHEMBL20924172 | 0.78 | KDM1A (0.49) | KDM1AMAOBTDP1L3MBTL1 | |
| SCHEMBL18034806 | 0.78 | MAP4K4 (0.51) | NOTUMMAP4K4KDM1AALOX5APMAPT | |
| SCHEMBL94256 | 0.74 | HDAC6 (0.50) | NOTUMMAP4K4ALOX5APMAPTKMT2A | |
| SCHEMBL94269 | 0.74 | MAP4K4 (0.55) | NOTUMMAP4K4ALOX5APMAPTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012013727-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |