SCHEMBL6837486

SCHEMBL6837486

O=C(O)C1CNC(C(=O)O)S1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.35
SLC1A2 P43004 4/20 0.32
SLC1A1 P43005 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP2D6 P10635 1/20 0.32
ALOX15 P16050 1/20 0.32
SLC1A3 P43003 1/20 0.32
SLC6A1 P30531 2/20 0.31
TSHR P16473 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
PKM P14618 1/20 0.31
SLC6A11 P48066 1/20 0.31
LMNA P02545 1/20 0.31
SLC6A13 Q9NSD5 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468398 0.72 TSHR (0.35) ERN1SLC1A2SLC1A1CYP1A2CYP2C19
SCHEMBL68915 0.68 TSHR (0.33) CYP1A2CYP2C19CYP2D6ALOX15TSHR
SCHEMBL2807157 0.68 TSHR (0.33) CYP1A2CYP2C19CYP2D6ALOX15TSHR
SCHEMBL28272389 0.64 CYP2D6 (0.43) SLC1A2SLC1A1CYP1A2CYP2C19CYP2D6
SCHEMBL69554 0.64 KDM4E (0.34) SLC6A1TSHRSMN1; SMN2SLC6A11LMNA
SCHEMBL28613071 0.64 KDM4E (0.34) SLC6A1TSHRSMN1; SMN2SLC6A11LMNA
SCHEMBL11408850 0.62 TSHR (0.33) CYP1A2CYP2C19CYP2D6ALOX15TSHR
SCHEMBL3370072 0.60
SCHEMBL3362598 0.59
SCHEMBL14506000 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6753383-B2 REDUCING FREE ALDEHYDES IN DISPERSIONS, SUSPENSIONS, EMULSIONS AND SOLUTIONS BY SCAVENGING WITH A THIOAMINE COMPOUND; ODORLESS; NONTOXIC; DISCOLORATION INHIBITION; TEXTILES; GASES CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2004-06-22 US disclosed