Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381831 | 0.85 | HDAC6 (0.68) | KDM4ENPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL1161248 | 0.84 | HDAC6 (0.62) | KDM4ENPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL29779499 | 0.82 | HDAC6 (0.61) | KDM4ENPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL3975423 | 0.82 | KDM4E (0.69) | KDM4ENPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL8861233 | 0.81 | HDAC6 (0.62) | KDM4ENPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL3976218 | 0.81 | HDAC6 (0.62) | KDM4ENPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL11428310 | 0.81 | HDAC6 (1.00) | KDM4ENPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL28669206 | 0.79 | HDAC6 (0.60) | KDM4ENPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL28490940 | 0.78 | HDAC6 (0.63) | KDM4ENPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL11368110 | 0.77 | HDAC6 (0.74) | KDM4ENPC1RAB9AHDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6761874-B2 | CATALYTIC HYDROGENATION OF 2-QUINOXALINONE COMPOUND | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-07-13 | — | — | US | disclosed |
| US-20030165421-A1 | Process for the preparation of hydrogen peroxide | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-09-04 | — | — | US | disclosed |