SCHEMBL6838477

SCHEMBL6838477

COc1nc(Cl)nc2c1ncn2C1OC(CO)C(O)C1(C)O

nearest known ligand 0.74

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 10/20 0.74
ADORA1 P30542 10/20 0.65
ADORA3 P0DMS8 8/20 0.65
ADORA2B P29275 7/20 0.65
ALOX15 P16050 1/20 0.65
ADA P00813 1/20 0.52
NT5E P21589 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19974564 0.89 ADORA2A (0.58) ADORA2AADORA1ADORA3ADORA2BALOX15
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL12939406 0.88 ADORA2A (0.66) ADORA2AADORA1ADORA3ADORA2BALOX15
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL19493379 0.88 ADORA2A (0.66) ADORA2AADORA1ADORA3ADORA2BALOX15
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL721333 0.88 ADORA2A (0.66) ADORA2AADORA1ADORA3ADORA2BALOX15
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL12219172 0.88 ADORA2A (0.66) ADORA2AADORA1ADORA3ADORA2BALOX15
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL14762374 0.88 ADORA2A (0.66) ADORA2AADORA1ADORA3ADORA2BALOX15
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL14816756 0.88 ADORA2A (0.66) ADORA2AADORA1ADORA3ADORA2BALOX15
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL15628197 0.88 ADORA2A (0.66) ADORA2AADORA1ADORA3ADORA2BALOX15
SCHEMBL15459916 0.88 ADORA2A (0.60) ADORA2AADORA1ADORA3ADORA2BALOX15
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL12194676 0.88 ADORA2A (0.66) ADORA2AADORA1ADORA3ADORA2BALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection GENELABS TECHNOLOGIES, INC. 2004-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection HAVCR2, PNP, NTPCR ADORA2A 174/4885ADORA1 522/4885ADORA3 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.