SCHEMBL68386

SCHEMBL68386

COc1cc(CCN)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 1.00
TSHR P16473 3/20 1.00
MAPK1 P28482 3/20 1.00
LMNA P02545 3/20 0.96
GLA P06280 1/20 0.96
CYP3A4 P08684 2/20 0.77
NFKB1 P19838 2/20 0.77
CYP1A2 P05177 1/20 0.77
APEX1 P27695 2/20 0.74
MEN1 O00255 1/20 0.74
KMT2A Q03164 1/20 0.74
KDM4E B2RXH2 3/20 0.72
ATM Q13315 1/20 0.72
PTPN1 P18031 2/20 0.69
ALOX5 P09917 2/20 0.63
OR51E2 Q9H255 1/20 0.63
TDP1 Q9NUW8 3/20 0.62
ALDH1A1 P00352 3/20 0.62
ADRA2A P08913 2/20 0.62
MAPT P10636 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365033 1.00 TAAR1 (1.00) TAAR1TSHRMAPK1LMNAGLA
Hydrochloric Acid SCHEMBL347598 0.98 TAAR1 (1.00) TAAR1TSHRMAPK1LMNAGLA
Hydrochloric Acid SCHEMBL15845572 0.96 TAAR1 (0.93) TAAR1TSHRMAPK1LMNAGLA
Dopamine SCHEMBL27902229 0.95 TAAR1 (0.90) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL28994052 0.93 TSHR (0.90) TAAR1TSHRMAPK1LMNAGLA
Sulfuric Acid SCHEMBL17157294 0.92 TAAR1 (0.84) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL11856815 0.91 TSHR (0.83) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL29604390 0.90 PTPN1 (0.82) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL17780116 0.90 PTPN1 (0.82) TAAR1TSHRMAPK1LMNAGLA
Hydrochloric Acid SCHEMBL16799321 0.90 TAAR1 (0.84) TAAR1TSHRMAPK1LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4333 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260148848-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-05-28 US claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
US-20260041336-A1 PLATELET REACTIVITY EXPRESSION SCORE PREDICTS CARDIOVASCULAR RISK NEW YORK UNIVERSITY (US) 2026-02-12 US claimed
US-20260002951-A1 METHOD FOR PROVIDING INFORMATION FOR BRAIN DOPING DIAGNOSIS KOREA INST SCI & TECH (KR) 2026-01-01 US claimed
CN-120192666-A Bio-based silica gel material and preparation method thereof 广东彩汇美新材料技术有限公司 2025-06-24 CN claimed
EP-4568660-A1 INHALABLE EPINEPHRINE FORMULATION De Motu Cordis Pty Ltd (AU) 2025-06-18 EP claimed
CN-120142546-A Method for detecting catecholamine and metabolite thereof in urine 中国科学技术大学 2025-06-13 CN claimed
CN-120121750-A Liquid chromatography tandem mass spectrometry detection method for catecholamine and metabolite thereof 上海拜谱生物科技有限公司 2025-06-10 CN claimed
EP-4562182-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2025-06-04 EP claimed
EP-1633348-A1 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES Elan Pharmaceuticals, Inc. (US) 2006-03-15 EP claimed
US-20050228001-A1 Methods and compositions for treating platelet-related disorders COMERICA BANK 2005-10-13 US claimed
US-20050020659-A1 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists ELAN PHARMACEUTICALS, INC. 2005-01-27 US claimed
WO-2004098589-A1 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES ELAN PHARMACEUTICALS, INC. (US) 2004-11-18 WO claimed
US-20040224031-A1 Combination of amines and vanadium (IV)/(V) compounds for the treatment and/or prevention of diabetes mellitus UNIVERSIDAD DE BARCELONA (ES) 2004-11-11 US claimed
US-20030191069-A1 2-oxoquinoline compounds and pharmaceutical uses thereof JAPAN TOBACCO, INC (JP) 2003-10-09 US claimed
EP-1338280-A1 COMBINATION OF AMINES AND VANADIUM (IV)/(V) COMPOUNDS FOR THE TREATMENT AND/OR PREVENTION OF DIABETES MELLITUS Universidad de Barcelona (ES) 2003-08-27 EP claimed
US-6509352-B1 Selectively act on cannabinoid receptors, particularly on peripheral type cannabinoid receptors, and have fewer side effects on the central nervous system, having great immunosuppressive action, anti-inflammatory action or JAPAN TOBACCO INC. (JP) 2003-01-21 US claimed
EP-1142877-A1 2-OXOQUINOLINE COMPOUNDS AND MEDICINAL USES THEREOF JAPAN TOBACCO INC. (JP) 2001-10-10 EP claimed
EP-0326329-B1 Quinazoline derivatives useful as insecticides. DOW AGROSCIENCES LLC (US) 1998-10-28 EP claimed