⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034321 | 0.78 | — | — | |
| SCHEMBL22171051 | 0.75 | — | — | |
| SCHEMBL19432260 | 0.72 | KMT2A (0.32) | — | |
| SCHEMBL8895047 | 0.69 | — | — | |
| Diethyl Sulfide SCHEMBL27651526 | 0.69 | TSHR (0.32) | — | |
| Diethyl Sulfide SCHEMBL27852396 | 0.69 | — | — | |
| SCHEMBL15432813 | 0.67 | — | — | |
| SCHEMBL13953026 | 0.67 | — | — | |
| SCHEMBL6747041 | 0.67 | — | — | |
| SCHEMBL1442971 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101100450-A | Method for preparing ethylsulfonyl acetonitrile | HUNAN CHEMICAL RES INST (CN) | 2008-01-09 | — | — | CN | claimed |
| CN-115850239-A | Synthetic method of rimsulfuron | 湖北荆洪生物科技股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-20180094016-A1 | Triazole Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-04-05 | — | — | US | disclosed |
| US-20180094016-A1 | Triazole Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-04-05 | — | — | US | disclosed |
| EP-2185547-B1 | IMIDAZOLONE DERIVATIVES, PREPARATION METHOD THEREOF AND BIOLOGICAL USE OF SAME | UNIV RENNES (FR) | 2017-07-19 | — | — | EP | disclosed |
| EP-1934238-B1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20170073359-A1 | Optically-Detectable Enzyme Substrates and Their Method of Use | MOLECULAR PROBES, INC. | 2017-03-16 | — | — | US | disclosed |
| EP-2997026-B1 | SUBSTITUTED ISOXAZOLE DERIVATIVES | BASF SE (DE) | 2017-03-15 | — | — | EP | disclosed |
| US-20160139135-A1 | Optically-Detectable Enzyme Substrates and Their Method of Use | LIFE TECHNOLOGIES CORP (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160031926-A1 | Triazole Compounds and Methods of Making and Using the Same | BioVersys AG (CH) | 2016-02-04 | — | — | US | disclosed |
| CN-101100450-A | Method for preparing ethylsulfonyl acetonitrile | HUNAN CHEMICAL RES INST (CN) | 2008-01-09 | — | — | CN | disclosed |
| WO-2007025284-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20040030093-A1 | Metal catalyst for ring-opening polymerization of heterocyclic compound | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1340780-A1 | METAL CATALYST FOR RING-OPENING POLYMERIZATION OF HETEROCYCLIC COMPOUND | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0734398-B1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2002-02-27 | — | — | EP | disclosed |
| US-5773512-A | Compounds and methods | SMITHKLINE BEECHAM CORP. (US) | 1998-06-30 | — | — | US | disclosed |
| US-4898874-A | Acetic acid derivatives of 3-aryl-2,1-benzisoxazole and esters and amides thereof | A. H. ROBINS COMPANY, INC. (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0260924-A1 | Antiinflammatory derivatives of 3-aryl-2,1-benzisoxazole | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4322351-A | Antineoplastic 4'-formylamino and 4'-acetylamino VLB, and derivatives thereof | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0046686-A1 | Derivatives of vincaleukoblastine, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-03 | — | — | EP | disclosed |