SCHEMBL6840785

SCHEMBL6840785

Nc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)O)cc(O)c12.[Na].[Na].[Na].[Na]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 1.00
ALDH1A1 P00352 4/20 0.58
HSD17B10 Q99714 4/20 0.58
CASP6 P55212 3/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
NSD2 O96028 3/20 0.53
DUSP3 P51452 1/20 0.53
PTPN5 P54829 1/20 0.53
PTPN11 Q06124 1/20 0.53
PTPN1 P18031 2/20 0.50
CYP1A2 P05177 2/20 0.49
PRMT1 Q99873 2/20 0.47
APEX1 P27695 1/20 0.47
GAA P10253 2/20 0.46
PLCG1 P19174 1/20 0.46
DNMT1 P26358 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HIF1A Q16665 1/20 0.46
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150291 1.00 NT5E (1.00) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL29415547 1.00 NT5E (1.00) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL564762 1.00 NT5E (1.00) NT5EALDH1A1HSD17B10CASP6CYP2C9
Hydroxyl Radical SCHEMBL28160622 0.98 NT5E (0.96) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL4870331 0.98 NT5E (0.96) NT5EALDH1A1HSD17B10CASP6CYP2C9
Water SCHEMBL31546582 0.98 NT5E (0.96) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL5637025 0.98 NT5E (0.96) NT5EALDH1A1HSD17B10CASP6CYP2C9
Water SCHEMBL12275537 0.96 NT5E (0.93) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL564761 0.90 NT5E (0.81) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL10535703 0.90 NT5E (0.81) NT5EALDH1A1HSD17B10CASP6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004015089-A2 POLYIONIC ORGANIC ACID FORMULATIONS GENTERIC, INC. (US) 2004-02-19 WO disclosed