Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7517423 | 1.00 | — | — | |
| Acetic Acid SCHEMBL27672369 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNMEN1KMT2A | |
| Acetic Acid SCHEMBL6855692 | 0.92 | — | — | |
| Acetic Acid SCHEMBL27506078 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNMEN1KMT2A | |
| Acetic Acid SCHEMBL28795718 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNMEN1KMT2A | |
| Acetic Acid SCHEMBL10595188 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNMEN1KMT2A | |
| Acetic Acid SCHEMBL28032779 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNMEN1KMT2A | |
| Acetic Acid SCHEMBL12544195 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNMEN1KMT2A | |
| Acetic Acid SCHEMBL28610104 | 0.92 | — | — | |
| Acetic Acid SCHEMBL28148899 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199249-A | Preparation method of micro-nano structure yttrium oxide with controllable structure morphology, product and application thereof | 长沙矿冶研究院有限责任公司 | 2023-06-02 | — | — | CN | disclosed |
| US-6770131-B2 | PREFERABLY THIN FILMS OF GALLIUM NITRIDE; DIRECT DEPOSITION OF AN AMORPHOUS LAYER OF A III-V COMPOUND PRECURSOR ON A SINGLE CRYSTAL SUBSTRATE; REACTION, CRYSTALLIZATION AND FORMATION OF FILMS BY PYROLYSIS. | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-08-03 | — | — | US | disclosed |
| US-20030012874-A1 | III-V compound films using chemical deposition | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2003-01-16 | — | — | US | disclosed |
| WO-2002040752-A2 | PROCESS FOR PRODUCING III-V COMPOUND FILMS BY CHEMICAL DEPOSITION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-05-23 | — | — | WO | disclosed |