SCHEMBL6841529

SCHEMBL6841529

C#CCO/N=C(C(/C)=N/OCc1ccccc1/C(=C\OC)C(=O)OC)\c1ccc(OCc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.45
HIF1A Q16665 2/20 0.44
NR4A2 P43354 1/20 0.42
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SPHK2 Q9NRA0 1/20 0.39
SPHK1 Q9NYA1 1/20 0.39
ADCYAP1R1 P41586 1/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7736847 1.00 MAOB (0.45) MAOBHIF1ANR4A2MAPTHTT
SCHEMBL7465781 0.92 MAOB (0.47) MAOBHIF1ANR4A2MAPTHTT
SCHEMBL7462687 0.92 MAOB (0.47) MAOBHIF1ANR4A2MAPTHTT
SCHEMBL7465783 0.92 MAOB (0.47) MAOBHIF1ANR4A2MAPTHTT
SCHEMBL6839881 0.92 HIF1A (0.53) MAOBHIF1ANR4A2MAPTHTT
SCHEMBL7493117 0.90 MAOB (0.45) MAOBHIF1ANR4A2MAPTHTT
SCHEMBL7497699 0.90 MAOB (0.45) MAOBHIF1ANR4A2MAPTHTT
SCHEMBL7497703 0.90 MAOB (0.45) MAOBHIF1ANR4A2MAPTHTT
SCHEMBL7493118 0.90 MAOB (0.45) MAOBHIF1ANR4A2MAPTHTT
SCHEMBL7500251 0.90 HIF1A (0.57) MAOBHIF1ANR4A2MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040039220-A1 Process for the preparation of pesticides FAROOQ SALEEM (CH) 2004-02-26 US disclosed
US-6646151-B1 Efficient oximation BAYER AKTIENGESELLSCHAFT (DE) 2003-11-11 US disclosed
EP-0876333-B1 PROCESS FOR THE PREPARATION OF PESTICIDES BAYER AG (DE) 2002-03-27 EP disclosed
US-6156923-A Process for the preparation of pesticides NOVARTIS CORPORATION (US) 2000-12-05 US disclosed
EP-0876333-A1 PROCESS FOR THE PREPARATION OF PESTICIDES Novartis AG (CH) 1998-11-11 EP disclosed
WO-1997020808-A1 PROCESS FOR THE PREPARATION OF PESTICIDES NOVARTIS AG (CH) 1997-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040039220-A1 Process for the preparation of pesticides CHRM1, CHRM2, F7 MAOB 28/4885HIF1A 3590/4885NR4A2 1581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.