Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 4/20 | 0.44 |
| ▸ | F10 | P00742 | 15/20 | 0.39 |
| ▸ | F2 | P00734 | 8/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645803 | 1.00 | PLAU (0.44) | PLAUF10F2PRSS1PLG | |
| SCHEMBL5649906 | 0.95 | PLAU (0.44) | PLAUF10F2PRSS1F7 | |
| SCHEMBL5647175 | 0.94 | PLAU (0.42) | PLAUF10F2PRSS1F7 | |
| SCHEMBL5647780 | 0.91 | PLAU (0.40) | PLAUF10F2PRSS1PLG | |
| SCHEMBL5645835 | 0.88 | PLAU (0.45) | PLAUF10F2PRSS1PLG | |
| SCHEMBL5645162 | 0.86 | PLAU (0.42) | PLAUF10F2PRSS1F7 | |
| SCHEMBL5647814 | 0.86 | FNTA (0.44) | PLAUF10F2PRSS1F7 | |
| SCHEMBL5647812 | 0.86 | PLAU (0.42) | PLAUF10F2PRSS1PLG | |
| SCHEMBL5650716 | 0.85 | PLAU (0.45) | PLAUF10F2PRSS1PLG | |
| SCHEMBL5646793 | 0.85 | F10 (0.39) | PLAUF10F2PRSS1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6773896-B2 | Method for direct measurement of coagulation factor VIIa activity in plasma | WARNER-LAMBERT COMPANY | 2004-08-10 | — | — | US | disclosed |
| EP-1260817-A2 | Method for direct measurement of coagulation factor VIIa activity in plasma | WARNER-LAMBERT COMPANY (US) | 2002-11-27 | — | — | EP | disclosed |
| US-20020168700-A1 | Method for direct measurement of coagulation factor VIIa activity in plasma | CHI LIGUO (US) | 2002-11-14 | — | — | US | disclosed |