SCHEMBL6843560

SCHEMBL6843560

CCCCCCCCCCCCCCCCCC(C)(C)[SiH2]O

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 5/20 0.45
GGPS1 O95749 6/20 0.41
FDPS P14324 9/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
CES2 O00748 1/20 0.39
LPAR1 Q92633 1/20 0.39
LPAR3 Q9UBY5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8755496 1.00 SMPD1 (0.45) SMPD1GGPS1FDPSTSHRTHRB
SCHEMBL8755460 1.00 SMPD1 (0.45) SMPD1GGPS1FDPSTSHRTHRB
SCHEMBL8756203 1.00 SMPD1 (0.45) SMPD1GGPS1FDPSTSHRTHRB
SCHEMBL6841738 1.00 SMPD1 (0.45) SMPD1GGPS1FDPSTSHRTHRB
SCHEMBL8756198 0.97 SMPD1 (0.42) SMPD1GGPS1FDPSCES2LPAR1
SCHEMBL8472572 0.79 TSHR (0.44) SMPD1GGPS1FDPSTSHRTHRB
SCHEMBL2119954 0.75 TSHR (0.40) SMPD1GGPS1FDPSTSHRTHRB
SCHEMBL2122750 0.75 TSHR (0.40) SMPD1GGPS1FDPSTSHRTHRB
SCHEMBL2124380 0.75 TSHR (0.40) SMPD1GGPS1FDPSTSHRTHRB
SCHEMBL2122250 0.75 TSHR (0.40) SMPD1GGPS1FDPSTSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10077279-B2 Vinylsilanes for use in functionalized elastomeric polymers TRINSEO EUROPE GMBH (CH) 2018-09-18 US disclosed
EP-3057974-B1 VINYLSILANES FOR USE IN FUNCTIONALIZED ELASTOMERIC POLYMERS TRINSEO EUROPE GMBH (CH) 2017-12-06 EP disclosed
US-20160264601-A1 Vinylsilanes for Use in Functionalized Elastomeric Polymers SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2016-09-15 US disclosed
EP-3057974-A1 VINYLSILANES FOR USE IN FUNCTIONALIZED ELASTOMERIC POLYMERS Trinseo Europe GmbH (CH) 2016-08-24 EP disclosed
WO-2015055252-A1 VINYLSILANES FOR USE IN FUNCTIONALIZED ELASTOMERIC POLYMERS TRINSEO EUROPE GMBH (CH) 2015-04-23 WO disclosed
US-6764807-B2 LITHOGRAPHY KODAK POLYCHROME GRAPHICS LLC 2004-07-20 US disclosed
US-20020086235-A1 Lithography EASTMAN KODAK COMPANY 2002-07-04 US disclosed
US-6399271-B1 HYDROXY CONTAINING COMPOUND WITH AFFINITY FOR INK, AND TITANIUM OR SILICON CONTAINING COMPOUND WITH DIFFERENT AFFINITY FOR INK KODAK POLYCHROME GRAPHICS LLC 2002-06-04 US disclosed
EP-1021301-A1 PLANOGRAPHIC PRINTING Kodak Polychrome Graphics Company Ltd. (US) 2000-07-26 EP disclosed
CN-1044476-C Chelate and preparation thereof NOVARTIS AG (CH) 1999-08-04 CN disclosed
EP-0635533-B1 Polyimide-based liquid crystal aligning agent SAGAMI CHEM RES (JP) 1998-06-10 EP disclosed
EP-0484857-B1 Polyorganosiloxane having a quaternary salt at its one terminal and percutaneous absorption-promoting agent SAGAMI CHEM RES (JP) 1997-05-07 EP disclosed
EP-0452725-B1 Fluorine containing diaminobenzene derivatives and its use SAGAMI CHEM RES (JP) 1995-11-08 EP disclosed
EP-0635533-A1 Polyimide-based liquid crystal aligning agent SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-01-25 EP disclosed
CN-1075966-A Inner complex and its preparation method CIBA GEIPY AG (CH) 1993-09-08 CN disclosed
US-5200488-A POLYORGANOSILOXANE HAVING A QUATERNARY SALT AT ITS ONE TERMINAL AND PERCUTANEOUS ABSORPTION-PROMOTING AGENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1993-04-06 US disclosed
US-5153304-A Polyimides; liquid crystal tilting agent; water-repelling SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-10-06 US disclosed
US-5144078-A Polyimide intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-09-01 US disclosed
EP-0484857-A2 Polyorganosiloxane having a quaternary salt at its one terminal and percutaneous absorption-promoting agent SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-05-13 EP disclosed
EP-0452725-A2 Fluorine containing diaminobenzene derivatives and its use SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264601-A1 Vinylsilanes for Use in Functionalized Elastomeric Polymers VIM, VCL, TERB1 SMPD1 4389/4885GGPS1 156/4885FDPS 104/4885
US-10077279-B2 Vinylsilanes for use in functionalized elastomeric polymers VIM, VCL, TERB1 SMPD1 4389/4885GGPS1 156/4885FDPS 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.