Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838796 | 0.92 | DPP4 (0.51) | TSHRMAPK1TP53HSD17B10DPP4 | |
| SCHEMBL6838716 | 0.91 | DPP4 (0.53) | TSHRMAPK1TP53HSD17B10DPP4 | |
| SCHEMBL6838791 | 0.90 | DPP4 (0.47) | TSHRMAPK1TP53HSD17B10DPP4 | |
| SCHEMBL6846144 | 0.90 | DPP4 (0.49) | TSHRMAPK1TP53HSD17B10DPP4 | |
| SCHEMBL3971305 | 0.89 | DPP4 (0.63) | TSHRMAPK1TP53HSD17B10DPP4 | |
| SCHEMBL6838812 | 0.89 | DPP4 (0.53) | TSHRMAPK1TP53HSD17B10DPP4 | |
| SCHEMBL6846148 | 0.89 | DPP4 (0.48) | TSHRMAPK1TP53HSD17B10DPP4 | |
| SCHEMBL3971184 | 0.88 | DPP4 (0.64) | TSHRMAPK1TP53HSD17B10DPP4 | |
| SCHEMBL6843487 | 0.87 | DPP4 (0.54) | TSHRMAPK1DPP4ALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL3973458 | 0.86 | DPP4 (0.56) | TSHRMAPK1TP53HSD17B10DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122228-A1 | New purine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122228-A1 | New purine derivatives, the preparation thereof and their use as pharmaceutical compositions | DPP4, DPP7, DPP3 | TSHR 2158/4885MAPK1 1025/4885TP53 4315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.