Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MTOR | P42345 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.62 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.50 |
| ▸ | POLA1 | P09884 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130206 | 1.00 | PDE3A (0.76) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL547055 | 0.89 | PDE3A (0.74) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL1880453 | 0.89 | PDE3A (0.74) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL18561536 | 0.88 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL21006620 | 0.88 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL15316783 | 0.88 | PDE3A (0.80) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL12149492 | 0.88 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL18537397 | 0.88 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL232223 | 0.88 | PDE3A (0.80) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL12151832 | 0.88 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250223620-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2025-07-10 | — | — | US | disclosed |
| EP-4504932-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2025-02-12 | — | — | EP | disclosed |
| CN-119013398-A | Novel method for producing polynucleotides comprising oligonucleotides | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023194537-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-12 | — | — | WO | disclosed |
| US-6762169-B1 | IMPROVED TRANSMEMBRANE DELIVERY OF NUCLEOSIDES CONJUGATED TO AN ARYLPROPIONIC ACID LIGAND (IBUPROFEN) WHICH HAS AFFINITY FOR PLASMA PROTEIN ALBUMIN; ANTISENSE THERAPY | ISIS PHARMACEUTICALS, INC. | 2004-07-13 | — | — | US | disclosed |
| US-6656730-B1 | Attached to an arylpropionic acid that interacts with human serum albumin; acid is ibuprofen, suprofen, ketoprofen, (S)-(+)- pranoprofen, or carprofen. | ISIS PHARMACEUTICALS, INC. | 2003-12-02 | — | — | US | disclosed |
| EP-1185305-A1 | LIGAND-CONJUGATED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000076554-A1 | LIGAND-CONJUGATED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2000-12-21 | — | — | WO | disclosed |