Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872655 | 1.00 | NR1H2 (0.37) | NR1H2NR1H3SMN1; SMN2PTPN1CYP3A4 | |
| SCHEMBL4870352 | 0.88 | HDAC8 (0.39) | NR1H2NR1H3SMN1; SMN2PTPN1CYP3A4 | |
| SCHEMBL5224049 | 0.88 | HSD17B10 (0.40) | NR1H2SMN1; SMN2HSD17B10HDAC8MEN1 | |
| SCHEMBL4864356 | 0.84 | NR1H2 (0.38) | NR1H2NR1H3SMN1; SMN2PTPN1CYP3A4 | |
| SCHEMBL10269862 | 0.82 | NR1H2 (0.41) | NR1H2NR1H3SMN1; SMN2PTPN1HSD17B10 | |
| SCHEMBL2127763 | 0.82 | NR1H2 (0.41) | NR1H2NR1H3SMN1; SMN2PTPN1HSD17B10 | |
| SCHEMBL30272143 | 0.82 | NR1H2 (0.41) | NR1H2NR1H3SMN1; SMN2PTPN1HSD17B10 | |
| SCHEMBL17973835 | 0.81 | HDAC8 (0.38) | NR1H2NR1H3SMN1; SMN2PTPN1CYP3A4 | |
| SCHEMBL5519647 | 0.81 | HDAC8 (0.37) | NR1H2NR1H3SMN1; SMN2PTPN1CYP3A4 | |
| SCHEMBL4871852 | 0.81 | HSD17B10 (0.39) | SMN1; SMN2HSD17B10HDAC8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040230046-A1 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230046-A1 | Lincomycin derivatives possessing antibacterial activity | NRDC, NISCH, CLSPN | NR1H2 3696/4885NR1H3 3855/4885SMN1; SMN2 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.