Carbimide

Carbimide

SCHEMBL6844293

N=C=N.NC(=O)NC(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.41
TSHR P16473 2/20 0.35
NFKB1 P19838 2/20 0.35
LMNA P02545 2/20 0.35
CYP1A2 P05177 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
THPO P40225 1/20 0.35
CA2 P00918 1/20 0.35
CYP3A4 P08684 1/20 0.35
CA5A P35218 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
CA9 Q16790 1/20 0.35
ACHE P22303 1/20 0.33
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbimide SCHEMBL11668505 0.97 CRBN (0.39) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL3418549 0.92 CRBN (0.39) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL8763414 0.92 CRBN (0.39) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL736167 0.92 CRBN (0.39) CRBNTSHRNFKB1LMNACYP1A2
Methane SCHEMBL19971268 0.89 CRBN (0.38) CRBNTSHRNFKB1LMNACYP1A2
Methane SCHEMBL8333924 0.89 CRBN (0.38) CRBNTSHRNFKB1LMNACYP1A2
Methane SCHEMBL676366 0.89 CRBN (0.38) CRBNTSHRNFKB1LMNACYP1A2
Hydrogen Peroxide SCHEMBL28780383 0.87
SCHEMBL9425846 0.87 CRBN (0.50) CRBNTSHRNFKB1LMNACYP1A2
SCHEMBL22493 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3268408-B1 POLYURETHANE MOLDED BODIES HAVING EXCELLENT FLEXIBILITY AT LOW TEMPERATURE BASF SE (DE) 2018-12-05 EP disclosed
CN-108699212-A Dual cure soft feel coating 阿科玛法国公司 2018-10-23 CN disclosed
US-20040018787-A1 Treated textile fabric HI-TEX, INC. 2004-01-29 US disclosed