Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 19/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.82 |
| ▸ | MME | P08473 | 2/20 | 0.82 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318275 | 1.00 | CTSA (0.82) | CTSACYP3A4MMEPTGS2 | |
| SCHEMBL6845234 | 0.90 | CTSA (1.00) | CTSACYP3A4MME | |
| SCHEMBL2317046 | 0.90 | CTSA (1.00) | CTSACYP3A4MME | |
| SCHEMBL2319815 | 0.89 | CTSA (0.69) | CTSACYP3A4MMEPTGS2 | |
| SCHEMBL14696564 | 0.89 | CTSA (0.69) | CTSACYP3A4MMEPTGS2 | |
| SCHEMBL2318283 | 0.89 | CTSA (0.85) | CTSACYP3A4MME | |
| SCHEMBL6845225 | 0.89 | CTSA (0.85) | CTSACYP3A4MME | |
| SCHEMBL2364019 | 0.86 | CTSA (0.76) | CTSACYP3A4MME | |
| SCHEMBL15636165 | 0.86 | CTSA (1.00) | CTSACYP3A4MME | |
| SCHEMBL2363766 | 0.85 | CTSA (0.78) | CTSACYP3A4MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092187-A1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2011-08-04 | — | — | WO | disclosed |