Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 20/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.81 |
| ▸ | MME | P08473 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6845145 | 1.00 | CTSA (0.81) | CTSACYP3A4MME | |
| SCHEMBL14696340 | 1.00 | CTSA (0.81) | CTSACYP3A4MME | |
| SCHEMBL2323823 | 1.00 | CTSA (0.81) | CTSACYP3A4MME | |
| SCHEMBL2320441 | 1.00 | CTSA (0.81) | CTSACYP3A4MME | |
| SCHEMBL15636388 | 0.96 | CTSA (0.85) | CTSACYP3A4MME | |
| SCHEMBL2323110 | 0.94 | CTSA (0.72) | CTSACYP3A4MME | |
| SCHEMBL14696601 | 0.94 | CTSA (0.72) | CTSACYP3A4MME | |
| SCHEMBL2319717 | 0.94 | CTSA (0.72) | CTSACYP3A4MME | |
| SCHEMBL2320648 | 0.94 | CTSA (0.71) | CTSACYP3A4MME | |
| SCHEMBL2322556 | 0.94 | CTSA (0.71) | CTSACYP3A4MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092187-A1 | OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2011-08-04 | — | — | WO | disclosed |