⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959418 | 0.80 | — | — | |
| SCHEMBL6846419 | 0.75 | — | — | |
| SCHEMBL641075 | 0.72 | — | — | |
| SCHEMBL5858895 | 0.67 | — | — | |
| SCHEMBL20394576 | 0.65 | — | — | |
| SCHEMBL10991808 | 0.64 | — | — | |
| SCHEMBL269083 | 0.64 | — | — | |
| SCHEMBL4959422 | 0.63 | — | — | |
| SCHEMBL18740711 | 0.63 | — | — | |
| SCHEMBL1094918 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018708-A | Synthesis method of difluoroalkyl substituted aromatic ketone compound under photocatalysis | 浙江工业大学 | 2020-04-17 | — | — | CN | claimed |
| CN-110803972-A | Synthesis method of difluoroalkyl substituted aromatic aldehyde compound under photocatalysis | 浙江工业大学 | 2020-02-18 | — | — | CN | claimed |
| US-20240239778-A1 | GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-07-18 | — | — | US | disclosed |
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2024140679-A1 | SPIROCYCLIC HPK1 ANTAGONISTS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-07-04 | — | — | WO | disclosed |
| EP-4392414-A1 | INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2024115733-A1 | FUSED PYRROLYL-SULFONAMIDE COMPOUNDS | REWIND THERAPEUTICS NV (BE) | 2024-06-06 | — | — | WO | disclosed |
| CN-118119619-A | SIK inhibitor and composition, preparation method and application thereof | 上海美悦生物科技发展有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-118119603-A | Substituted benzamides as herbicides | 先正达农作物保护股份公司 | 2024-05-31 | — | — | CN | disclosed |
| US-10220034-B2 | Hepatitis B viral assembly effectors | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2019-03-05 | — | — | US | disclosed |
| CN-108884050-A | Tetrahydroisoquinoline derivatives | UCB生物制药私人有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-107108672-A | The five rings imdazole derivatives of fusion | UCB生物制药私人有限公司 | 2017-08-29 | — | — | CN | disclosed |
| WO-2017012647-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | GALAPAGOS NV (BE) | 2017-01-26 | — | — | WO | disclosed |
| US-20160271130-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (US) | 2016-09-22 | — | — | US | disclosed |
| WO-2015142670-A1 | ANTI-DIABETIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND METHOD TO TREAT DIABETES | MEDISYN TECHNOLOGIES, INC. (US) | 2015-09-24 | — | — | WO | disclosed |
| US-6777433-B2 | BIS((DIFLUORO-PHOSPHONATO-METHYL)PHENYL) DERIVATIVES; ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2004-08-17 | — | — | US | disclosed |
| US-20030114703-A1 | Protein tyrosine phosphatase 1B (PTP-1B) inhibitors containing two ortho-substituted aromatic phosphonates | MERCK FROSST CANADA LTD. (CA) | 2003-06-19 | — | — | US | disclosed |
| US-5599639-A | Acid-modified polybenzimidazole fuel cell elements | HOECHST CELANESE CORPORATION (US) | 1997-02-04 | — | — | US | disclosed |