Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906583 | 0.75 | F2 (0.52) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7737891 | 0.72 | F2 (0.54) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL4904924 | 0.69 | F2 (0.67) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL14281097 | 0.68 | F2 (0.68) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6846360 | 0.68 | F2 (0.58) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7448903 | 0.68 | F2 (0.60) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6846386 | 0.68 | F2 (0.55) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL4898740 | 0.67 | F2 (0.63) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7066282 | 0.67 | F2 (0.58) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6850252 | 0.66 | F2 (0.56) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |