Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 9/20 | 0.83 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6753340 | 0.99 | F2R (0.81) | F2RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL12393183 | 0.91 | F2R (1.00) | F2RMAPTKMT2AMEN1KDM4E | |
| Bromide SCHEMBL6751238 | 0.90 | F2R (0.68) | F2RMAPTKMT2AMEN1KDM4E | |
| Bromide SCHEMBL2351227 | 0.90 | F2R (0.98) | F2RMAPTKMT2AMEN1KDM4E | |
| Bromide SCHEMBL6752584 | 0.89 | F2R (0.77) | F2RMAPTKMT2AMEN1KDM4E | |
| SCHEMBL6846941 | 0.88 | F2R (0.78) | F2RMAPTKMT2AMEN1KDM4E | |
| Bromide SCHEMBL6751125 | 0.87 | F2R (0.77) | F2RMAPTKMT2AMEN1KDM4E | |
| Bromide SCHEMBL6751231 | 0.87 | F2R (0.80) | F2RMAPTKMT2AMEN1KDM4E | |
| Bromide SCHEMBL6751213 | 0.86 | F2R (0.86) | F2RMAPTKMT2AMEN1KDM4E | |
| Bromide SCHEMBL6750288 | 0.86 | F2R (0.86) | F2RMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394152-A1 | 2-IMINOIMIDAZOLE DERIVATIVES (1) | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |