Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29285234 | 0.94 | TSHR (0.50) | TSHRACHETDP1MEN1KMT2A | |
| SCHEMBL13081648 | 0.83 | TSHR (0.42) | TSHRACHEPPARDKMT2A | |
| SCHEMBL15977306 | 0.81 | TSHR (0.56) | TSHRACHEPPARDTP53TDP1 | |
| SCHEMBL7006853 | 0.81 | TSHR (0.56) | TSHRACHEPPARDTP53TDP1 | |
| SCHEMBL28068076 | 0.80 | TSHR (0.39) | TSHRACHETDP1MEN1KMT2A | |
| SCHEMBL5961215 | 0.79 | TSHR (1.00) | TSHRACHEPPARDTP53TDP1 | |
| SCHEMBL26483 | 0.79 | TSHR (1.00) | TSHRACHEPPARDTP53TDP1 | |
| SCHEMBL872150 | 0.78 | TSHR (0.68) | TSHRACHEPPARDTP53TDP1 | |
| SCHEMBL491513 | 0.78 | TSHR (0.54) | TSHRACHEPPARDTP53TDP1 | |
| SCHEMBL585292 | 0.78 | TSHR (0.75) | TSHRACHEPPARDTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087633-A1 | Methylidene oxazolidinone compound and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-05-06 | — | — | US | disclosed |
| US-4276409-A | USED FOR CHELATING METALLIC IONS | OCCIDENTAL RESEARCH CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087633-A1 | Methylidene oxazolidinone compound and preparation method thereof | OXA1L, TET1, TET2 | TSHR 4600/4885ACHE 4776/4885PPARD 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.