Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 4/20 | 0.34 |
| ▸ | FLT4 | P35916 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | FBP1 | P09467 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804322 | 0.87 | CCR4 (0.41) | CCR4CCKBRKMT2AFLT1FLT4 | |
| SCHEMBL6807253 | 0.80 | CCR4 (0.40) | CCR4CCKBRKMT2A | |
| SCHEMBL7562585 | 0.78 | CCR4 (0.48) | CCR4CCKBRKMT2AFLT1FLT4 | |
| SCHEMBL1548108 | 0.78 | CCR4 (0.41) | CCR4CCKBRKMT2ATDP1CA12 | |
| SCHEMBL7567612 | 0.77 | CCR4 (0.42) | CCR4CCKBRKMT2AFLT1FLT4 | |
| SCHEMBL6802957 | 0.77 | CCR4 (0.38) | CCR4CCKBR | |
| SCHEMBL6807252 | 0.75 | CCR4 (0.40) | CCR4CCKBRKMT2AFBP1MEN1 | |
| SCHEMBL2914947 | 0.74 | DAO (0.41) | CCR4CCKBRKMT2AFBP1TDP1 | |
| Hydrochloric Acid SCHEMBL27779746 | 0.73 | DAO (0.39) | CCR4CCKBRKMT2ATDP1DAO | |
| SCHEMBL390902 | 0.72 | CCR4 (0.40) | CCR4CCKBRKMT2AFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412364-A1 | PLATELET ADP RECEPTOR INHIBITORS | Portola Pharmaceuticals, Inc. (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011872-A1 | PLATELET ADP RECEPTOR INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-02-13 | — | — | WO | disclosed |