Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TLR4 | O00206 | 1/20 | 0.57 |
| ▸ | TLR2 | O60603 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 7/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863665 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB | |
| SCHEMBL3904389 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB | |
| SCHEMBL10497495 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB | |
| SCHEMBL10497778 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB | |
| SCHEMBL8796357 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB | |
| SCHEMBL6289516 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB | |
| SCHEMBL10498103 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB | |
| SCHEMBL584475 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB | |
| SCHEMBL7756955 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB | |
| SCHEMBL584671 | 1.00 | TSHR (0.59) | TSHRTLR4TLR2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107971-B1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LTD (GB) | 2004-11-24 | — | — | EP | disclosed |
| US-6630128-B1 | Insoluble support | DESTINY PHARMA LIMITED (GB) | 2003-10-07 | — | — | US | disclosed |
| EP-1107971-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | Destiny Pharma Limited (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012512-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| US-4187319-A | HYDROCARBYLTHIO-SUBSTITUTED | RICHARDSON-MERRELL INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4066788-A | Substituted benzaldehyde hypolipidemic agents | RICHARDSON-MERRELL INC. (US) | 1978-01-03 | — | — | US | disclosed |