Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.45 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | CYCS | P99999 | 4/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850253 | 1.00 | PDE3B (0.45) | PDE3BPDE3AP2RY12TOP1CYCS | |
| SCHEMBL6851379 | 1.00 | PDE3B (0.45) | PDE3BPDE3AP2RY12TOP1CYCS | |
| SCHEMBL6851842 | 1.00 | PDE3B (0.45) | PDE3BPDE3AP2RY12TOP1CYCS | |
| SCHEMBL6850167 | 0.92 | PDE3B (0.43) | PDE3BPDE3AP2RY12TOP1CYCS | |
| SCHEMBL6847228 | 0.92 | PDE3B (0.43) | PDE3BPDE3AP2RY12TOP1CYCS | |
| SCHEMBL6850223 | 0.92 | PDE3B (0.43) | PDE3BPDE3AP2RY12TOP1CYCS | |
| SCHEMBL6851454 | 0.92 | PDE3B (0.43) | PDE3BPDE3AP2RY12TOP1CYCS | |
| SCHEMBL6847328 | 0.92 | PDE3B (0.43) | PDE3BPDE3AP2RY12TOP1CYCS | |
| SCHEMBL6850181 | 0.92 | PDE3B (0.43) | PDE3BPDE3AP2RY12TOP1CYCS | |
| SCHEMBL6851518 | 0.92 | PDE3B (0.43) | PDE3BPDE3AP2RY12TOP1CYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107971-B1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LTD (GB) | 2004-11-24 | — | — | EP | disclosed |
| US-6630128-B1 | Insoluble support | DESTINY PHARMA LIMITED (GB) | 2003-10-07 | — | — | US | disclosed |
| EP-1107971-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | Destiny Pharma Limited (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012512-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |