Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356481 | 0.81 | TDP1 (0.45) | TDP1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL8157644 | 0.80 | TDP1 (0.42) | TDP1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL7659602 | 0.80 | TDP1 (0.56) | TDP1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL11655565 | 0.80 | TDP1 (0.56) | TDP1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL18291061 | 0.79 | TDP1 (0.43) | TDP1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL15183509 | 0.79 | TDP1 (0.49) | TDP1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL6901399 | 0.78 | TDP1 (0.55) | TDP1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL21073906 | 0.78 | TDP1 (0.55) | TDP1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL2224230 | 0.76 | TDP1 (0.54) | TDP1KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL1562155 | 0.76 | TDP1 (0.50) | TDP1KMT2AMEN1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| US-5763481-A | PESTICIDES; INSECTICIDES, MITICIDES | NOVARTIS CORPROATION (US) | 1998-06-09 | — | — | US | disclosed |
| US-5545630-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0661289-A1 | Vinyl carboxamide derivatives as insecticides and acaricides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |