Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | CA9 | Q16790 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24664899 | 1.00 | TDP1 (0.67) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL12341542 | 0.98 | MEN1 (0.65) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL14405152 | 0.93 | MEN1 (0.72) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL18857298 | 0.90 | TDP1 (0.67) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL4378110 | 0.88 | TDP1 (0.65) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL137629 | 0.87 | TDP1 (0.85) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL3025184 | 0.87 | TDP1 (0.85) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL134329 | 0.87 | TDP1 (0.85) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL5162656 | 0.87 | TDP1 (0.85) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL136815 | 0.87 | TDP1 (0.85) | TDP1MEN1KMT2AGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3461835-A1 | CYCLOSPORINE ANALOGUE MOLECULES MODIFIED AT AMINO ACID 1 AND 3 | ContraVir Pharmaceuticals, Inc. (US) | 2019-04-03 | — | — | EP | disclosed |
| EP-2457923-B1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO LTD (JP) | 2016-01-27 | — | — | EP | disclosed |
| US-20150119585-A1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD (JP) | 2015-04-30 | — | — | US | disclosed |
| US-8952003-B2 | Sterol derivative | KYOWA HAKKO KIRIN CO., LTD (JP) | 2015-02-10 | — | — | US | disclosed |
| US-20120172348-A1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| EP-2457923-A1 | STEROL DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-7893265-B2 | Imidation of derivatives of anthracene-2,3:6,7-dianhydride, napthalene-1,4:5,8-dianhydride, or perylene-3,4:9,10-anhydride with primary amine to perylene-bis(dicarboximide)s, naphthalene-bis(dicarboximide)s, and anthracene-bis(dicarboximide)s and/or coronene-bis(dicarboximide)s; electronics, composites | POLYERA CORPORATION (US) | 2011-02-22 | — | — | US | disclosed |
| WO-2011010682-A1 | STEROL DERIVATIVE | 協和発酵キリン株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |
| US-20080177073-A1 | Methods for preparing arene-BIS (dicarboximide)-based semiconducting materials and related intermediates for preparing same | USINVEST LLC | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177073-A1 | Methods for preparing arene-BIS (dicarboximide)-based semiconducting materials and related intermediates for preparing same | RECQL, CCNE2, CCNE1 | TDP1 2134/4885MEN1 658/4885KMT2A 1140/4885 |
| US-20120172348-A1 | STEROL DERIVATIVE | NR1H3, NR1H2, SREBF1 | TDP1 3878/4885MEN1 1732/4885KMT2A 3380/4885 |
| US-20150119585-A1 | STEROL DERIVATIVE | NR1H3, NR1H2, SREBF1 | TDP1 3878/4885MEN1 1732/4885KMT2A 3380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.