SCHEMBL6848604

SCHEMBL6848604

CC#Cc1csc2cnc(C(=O)NC3CC4CCN3C4)cc12

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 5/20 0.41
HTR3A P46098 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6851281 0.89 CHRNA7 (0.41) CHRNA7HTR3A
SCHEMBL6849233 0.89 CHRNA7 (0.40) CHRNA7HTR3A
SCHEMBL6849707 0.89 CHRNA7 (0.40) CHRNA7HTR3A
SCHEMBL6844616 0.89 CHRNA7 (0.42) CHRNA7HTR3A
SCHEMBL6849152 0.89 CHRNA7 (0.42) CHRNA7HTR3A
SCHEMBL6849580 0.88 CHRNA7 (0.39) CHRNA7HTR3A
SCHEMBL6844656 0.88 CHRNA7 (0.39) CHRNA7HTR3A
SCHEMBL6848354 0.87 CHRNA7 (0.41) CHRNA7HTR3A
SCHEMBL843737 0.86 CHRNA7 (0.58) CHRNA7HTR3A
SCHEMBL843738 0.86 CHRNA7 (0.58) CHRNA7HTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1432707-A1 AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE PHARMACIA & UPJOHN COMPANY (US) 2004-06-30 EP claimed
WO-2003029252-A1 AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE PHARMACIA & UPJOHN COMPANY (US) 2003-04-10 WO claimed