Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16683729 | 1.00 | CDK5 (0.32) | CDK5CDK5R1KMT2A | |
| SCHEMBL9290695 | 1.00 | CDK5 (0.32) | CDK5CDK5R1KMT2A | |
| SCHEMBL10261160 | 1.00 | CDK5 (0.32) | CDK5CDK5R1KMT2A | |
| SCHEMBL15112165 | 0.78 | CDK5 (0.31) | CDK5CDK5R1KMT2A | |
| SCHEMBL15112163 | 0.78 | CDK5 (0.31) | CDK5CDK5R1KMT2A | |
| SCHEMBL936189 | 0.78 | CDK5 (0.31) | CDK5CDK5R1KMT2A | |
| SCHEMBL32686646 | 0.77 | CDK5 (0.33) | CDK5CDK5R1KMT2A | |
| Hydrochloric Acid SCHEMBL15411561 | 0.76 | KMT2A (0.33) | CDK5CDK5R1KMT2A | |
| SCHEMBL21562528 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL15112167 | 0.76 | KMT2A (0.33) | CDK5CDK5R1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172348-A1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| WO-2011010682-A1 | STEROL DERIVATIVE | 協和発酵キリン株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172348-A1 | STEROL DERIVATIVE | NR1H3, NR1H2, SREBF1 | CDK5 4144/4885CDK5R1 3179/4885KMT2A 3380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.