Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848865 | 1.00 | PARP1 (0.35) | PARP1CECR2PDE3BPDE3ADRD2 | |
| SCHEMBL7556544 | 0.81 | NR3C2 (0.46) | PDE3BPDE3APGRNR3C2 | |
| SCHEMBL6843953 | 0.80 | — | — | |
| SCHEMBL6843956 | 0.80 | — | — | |
| SCHEMBL7749245 | 0.79 | — | — | |
| SCHEMBL6848020 | 0.77 | — | — | |
| SCHEMBL6848017 | 0.77 | — | — | |
| SCHEMBL8565740 | 0.77 | NR3C2 (0.46) | PGRNR3C2 | |
| SCHEMBL6849418 | 0.73 | GAA (0.31) | — | |
| SCHEMBL6849421 | 0.73 | GAA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770596-B1 | Fused tricyclic compounds, process for their preparation, and herbicidal compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| WO-2000073277-A1 | FUSED TRICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND HERBICIDAL COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-12-07 | — | — | WO | disclosed |