Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 10/20 | 0.66 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5585203 | 0.99 | F2R (0.65) | F2RMAOBBCHEMAOAACHE | |
| SCHEMBL14346249 | 0.90 | F2R (0.69) | F2RMAOBBCHEMAOAACHE | |
| Bromide SCHEMBL4351865 | 0.89 | F2R (0.67) | F2RMAOBBCHEMAOAACHE | |
| SCHEMBL14346256 | 0.87 | F2R (0.67) | F2RMAOBBCHEMAOAACHE | |
| Bromide SCHEMBL4340591 | 0.86 | F2R (0.66) | F2RMAOBBCHEMAOAACHE | |
| SCHEMBL14368562 | 0.85 | F2R (0.55) | F2RMAOBBCHEMAOAACHE | |
| SCHEMBL14346324 | 0.84 | F2R (0.64) | F2RMAOBBCHEMAOAACHE | |
| SCHEMBL14346327 | 0.84 | F2R (0.64) | F2RMAOBBCHEMAOAACHE | |
| Bromide SCHEMBL4347358 | 0.83 | F2R (0.63) | F2RMAOBBCHEMAOAACHE | |
| SCHEMBL14346287 | 0.83 | F2R (0.63) | F2RMAOBBCHEMAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304083-B2 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |
| EP-1391456-A1 | 2-IMINOIMIDAZOLE DERIVATIVE (2) | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |